What’s the Role of Gluten in Celiac Disease and Type 1 Diabetes? –

If celiac disease is left untreated, complications ranging from iron deficiency to osteoporosis to cancer may develop. N Engl J Med 346: 180-188. Autoimmune thyroiditis is the most frequent disorder and appears to affect 39% of adult patients. Celiac disease is estimated to affect about 1 percent of U.S. If only children with biochemically defined diabetes-associated autoantibodies against insulin, GAD, or IA-2A protein (n = 146) and children with tissue transglutaminase autoantibodies were compared (n = 86), the median seroconversion ages were 2.5 and 3.0 years (P = 0.011). If you have a chronic condition such as diabetes or high blood pressure, “healthy” also means that you are being treated and the condition is under control. Family studies show that 5 percent of first-degree relatives of a person with DH will also have DH.

A health care professional may take a blood sample from you and send the sample to a lab to test for antibodies common in celiac disease. However, a recent study in the United States and Canada underscores the need for an uniform screening program. In conclusion, significant reservoirs of CD can be found in some at-risk groups, such as those with T1DM, family members, and referred patients with osteoporosis and anemia. We will ask that you or your child provide a blood sample during your routine diabetes clinic visit.