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Undiagnosed coeliac disease and risk of autoimmune disorders in subjects with Type I diabetes mellitus.


If it weren’t for the immune system—the human body’s natural defense against outside invaders—we would be sick all the time. A study published in Nature, carried out by the group of Dr. Public health measures aimed at the modern pro-inflammatory environment are required to stem the rising tide not only of T1D but other autoimmune and chronic inflammatory disorders. Results 37 eligible intervention trials of hydrolysed formula were identified, including over 19 000 participants. The major role of autoreactive T lymphocytes has been demonstrated in animal models of spontaneous insulin-dependent diabetes (the BB rat and the NOD mouse). They also observed that Faustman’s protocol could be used to reverse Sjögren’s syndrome, another autoimmune disease, in mice. Although the binding of antigens to different HLA molecules has been extensively studied, why some HLA haplotypes are positively associated and others negatively associated with type 1 diabetes is not clear.

However, family members can be affected by different disorders; for example, one person may have diabetes, while another has rheumatoid arthritis. Santamaria’s study shows that nanoparticles (particles thousands of times smaller than a typical cell), decorated with protein targets acting as “bait” for disease-causing white blood cells, can be used to reprogram them to suppress the disease they intended to cause. An accomplished neurologist from Harvard Medical School in Boston, Massachusetts, who specialized in behavioral disorders, Dr.