The risk appears even higher for those born with a cyanotic congenital heart disease (CHD) condition — one in which patients had a bluish coloration of the skin due to low oxygen content in tissues near the surface of the skin. Rates of all-cause and CHD mortality were compared in these groups. A 6-year prospective study also assessed the probability of developing Type 2 diabetes. Mean age at baseline was 59.8 (SD = 12.3) years with a mean diabetes duration of 10.6 (SD = 9.1) years; 56.7% were female, 39.7% were non-Hispanic White, and nearly 18% were smokers. Similarly, weight loss in overweight patients with established CHD improves risk factors, and reduces symptoms of angina and fatigue. The finding are similar to those seen in a smaller analysis of 37 studies reported by the researchers in 2006. Patients with high-density lipoprotein levels less than 40 mg/dL may benefit from fibrate therapy.
Of 25,739 participants analyzed, 11.8% had CHD only, 15.6% had diabetes