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Provocation of Postural Hypotension by Insulin in Diabetic Autonomic Neuropathy

OBJECTIVE—The aim of this study was to investigate the relationship between pre-diabetes and orthostatic hypotension and to examine the prevalence and correlates of orthostatic hypotension in community dwellers with normal glucose tolerance (NGT), pre-diabetes, and diabetes. The magnitude of this decrease in BP is related to the rate of gastric emptying (GE). Blood pressure decreased precipitously in the standing position in the diabetics with orthostatic hypotension, whereas moderate decreases were found in the other three groups. Association of OH with macrovascular and microvascular complications was evaluated and the effect of OH on 10-year all-cause mortality was also assessed.OH was present in 31.7% of patients with diabetes type 1 (DM1) and in 32.3% of patients with diabetes type 2 (DM2). Therapeutic strategies include: patient education and perfect supervision by dialysis staff dialysis procedure-related methods (extension of dialysis duration, low dialysate

Rory McCrimmon – Diabetes UK


People who only have severe hypoglycaemia when they are asleep (and would not be driving) should not lose their driving licence. Take supplies and make contingency plans. The parents’ fear was also associated with higher frequency of problematic hypoglycaemic episodes in the past year. These are shown in table 1. He has published extensively, particularly in this field, and has co-edited two multi-author international textbooks on hypoglycaemia and diabetes: Hypoglycaemia and Diabetes: Clinical and Physiological Aspects, and Hypoglycaemia in Clinical Diabetes (third edition). He chaired the glucose control group of the ADVANCE trial and is a steering committee member of the EXAMINE trial. I confess I was slightly surprised at the findings.

Professor Rory McCrimmon and his team will study the role of interleukin-6 in the body’s response to hypoglycaemia and its role in adapting the brain to repeated hypoglycaemia. This lecture will propose that glucose-sensing cells

Critical illness cover for diabetics: How does this work?

The present study assessed the centrality of one’s illness self-concept, or the degree to which chronic illness intrudes upon one’s self, in a sample of 478 18-35-year-old patients with Type 1 diabetes. and Johansson, A. The aim of this qualitative study was to investigate Chinese diabetic patients’ perceptions about their illness and treatment strategies to facilitate patient-centred, culture-sensitive clinical skills. The systematic search yielded 30 articles. Marvelous new therapeutic techniques often do not conquer or eradicate diseases but, instead, transform them. Three main themes were identified, including how the youths conceptualized the impact of T2DM, adjustment to self-care, and motivation to perform self-care behaviors. T2DM patients in the first years of their illness are often recommended to make lifestyle changes in the absence of noticeable diabetes-related symptoms or complaints.

This is because mental illness may affect capacity to participate

Fasting glucose, diagnosis of type 2 diabetes, and depression: the Vietnam experience study. – PubMed

Data concerning 13,845 subjects, aged 40–69 years, who had their FPG measured at least three times between 1992 and 2008 were extracted from a database. As this test may be unpleasant, time-consuming and has resource implications, we evaluated whether the 6-week postnatal fasting glucose could be used to determine which women should undergo an OGTT. Subjects were evaluated at baseline and after two years follow up. Homeostasis model assessment (HOMA) of insulin sensitivity (HOMA-%S) and beta-cell function (HOMA-%B) were calculated based on fasting glucose and insulin concentrations. Diabetes Control and Complications Trial-aligned HbA(1c) was 6.2% (5.8-6.6%) (reference interval < 6.0%) and FPG 6.7 mmol/l (6.3-7.2 mmol/l). Ninety-five (15.2%) individuals had diabetes based on the 2HPG alone, 62 (9.9%) based on the FPG alone and 168 (26.9%) based on both the FPG and 2HPG. According to WHO 1998 criteria, the patients were divided into groups due to glucose tolerance abnormalities. Fasting plasma glucose at was the most efficient investigation at cutoff of 5.1 mmol/L sensitivity=66.66%, specificity=81.25%, PPV=70%, NPV=78.78%, LR+=3.56, LR-=0.41, efficiency=75.47%.