Metformin is the first-line oral hypoglycemic agent for type 2 diabetes mellitus recommended by international guidelines. Subjects were randomised to either placebo or acarbose 50 mg t.i.d. The primary outcome measure was the time to develop a cardiovascular event. 9323:2072-2077), show that, overall, there was a 25 percent reduction in the incidence of type 2 diabetes mellitus during the course of the trial among IGT patients taking acarbose. 1999 Jun; 22:960-4. Whether hypertension had been diagnosed by the family physician was not documented. Mean 2-h post-prandial plasma glucose (PPG) value and fasting blood glucose (FBG) decreased from 243.9 to 169.5 mg/dl and 158.3 to 120.4 mg/dl, respectively after the last follow-up of 12.4 weeks.
Both acarbose and metformin are widely used as treatment for type 2 diabetes, and acarbose, in particular, is used extensively in China and other Asian countries, the authors noted in their introduction. RESULTS: At 3 years, a lower proportion of patients were taking acarbose compared with placebo (39 vs. 31, 2010. 12%, P < 0.0001) and diarrhea (16 vs. 8%, P < 0.05). Analysis by intention to treat showed that patients allocated to acarbose, compared with placebo, had 0.2% significantly lower median HbA1c at 3 years (P < 0.001). These should decrease as you continue to take the medication.
8.6%, P < 0.0001). Acarbose appeared to be equally efficacious when given in addition to diet alone; in addition to monotherapy with a sulfonylurea, metformin, or insulin; or in combination with more complex treatment regimens. Maintaining glycaemic control with Glucobay tablets 50mg reduces risk of serious health complications associated with diabetes, including diabetic retinopathy (damage to the retina in the eye with loss of vision), diabetic neuropathy (nerve damage) and diabetic nephropathy (kidney damage). 125–131. Of the eight million people diagnosed with diabetes, nearly 7.5 million have type 2 diabetes, and most of them require oral medication alone or in combination with insulin to keep blood sugar levels under control.