Background: Diabetes mellitus and hyperlipidemia are the most common metabolic disorder affecting the people all over the world. There is little information on the clinical profile and outcome of children with diabetic ketoacidosis in India. Electrical neutrality is maintained by equating + and – charged particles between ICF and ECF. Maintaining this difference, or gradient, across cell membranes is a major part of the complex regulatory events called homeostasis that keep conditions within the body stable within very narrow limits. STZ-diabetic rats progressively lost weight from the first to the third week but gained weight in the fourth week. This suggests that in diabetes mellitus, body sodium is increased. Vitex doniana belongs to the family verbenaceae and it is widely distributed in the tropical countries of Africa like Nigeria.
However, an effect of hypersomatostatinaemia or the hormonal changes associated with this cannot be excluded, while short-term hyperglycaemia