The concept of using phytochemicals has ushered in a new revolution in pharmaceuticals. Using accumulation of ED-1 as a marker of macrophage activation, we have demonstrated increased activation of macrophage in the glomeruli of kidney tissue from diabetic animals. We found that dietary curcumin admixture ameliorated diabetes in high-fat diet-induced obese and leptin-deficient ob/ob male C57BL/6J mice as determined by glucose and insulin tolerance testing and hemoglobin A1c percentages. I’m not getting paid to write this article by some supplement maker. A recent review study of more than 700 clinical trials involving curcumin and cancer found curcumin to be as effective as pharmaceutical drugs in treating cancers of the prostate, colon, breast, liver, esophagus, and mouth. Linda, turmeric is indeed a hotbed of research. Type-1 diabetes was induced by intraperitoneal injection of streptozotocin.
Sodium nitroprusside (SNP)-induced relaxation was unaltered up to initial stage