Lipohypertrophy Development of a ‘buffalo hump’ or increased dorso-cervical fat pad. Too much cortisol can result in fatty hump between the shoulders, a rounded face and pink or purple stretch marks on the skin. One-half occur as part of the Carney complex. The adrenal glands are stimulated to produce cortisol by another hormone (called ACTH) which is released by the pituitary gland, a very small gland located in the lower part of the brain. Cushing’s syndrome and Cushing’s disease are both conditions that occur when the body produces too much cortisol. Corticosteroids are usually prescribed in relatively low doses as they are known to cause side-effects; however, if a patient fails to respond to other treatments a long term dose or a higher dose may be required. Right above the pituitary gland, in the base of the brain, is the hypothalamus.
Although still rare, the prevalence of Cushing’s syndrome is increasing. Fasting glycaemia was the only