If you do need long-term oral steroids, it’s important to know the serious adverse effects you could face. We calculated adjusted hazard rate ratios considering exposure to systemic, inhaled, and topical PC’s separately in relationship to offspring diabetes. Pregnancy is also characterized by a relative insulin resistance that results in glucose intolerance. Corticosteroids may cause infections such as chickenpox or measles to be more serious in children who catch them. The initial studies were conducted upon 6 patients of the Mayo Clinic who were hospitalized for treatment of diabetic acidosis. Cortisol enhances the expression of 11 beta-HSD 1, and also of angiotensinogen and angiotensin type 1 receptors. Although, in fact graft and patient survival were significantly better in steroid-free patients, the authors comment that the difference was slight and cannot be presumed to be related to steroids because of the retrospective registry-based nature of the study.