Prospective study over 10 years of 25 non-diabetic identical twins of patients with insulin dependent diabetes. The ADDITION-PRO study included 1,462 participants who had normal glucose tolerance (n=774), pre-diabetes (n=523), or screen-detected type 2 diabetes (n=163). We are sicker than we have ever been in the history of humans. Our idea was to create a model that resembles the situation in the development of type 2 diabetes in humans. Hormones that help your baby develop during pregnancy may prevent insulin from working normally in your body. “There’s this yin and yang between fat and sugars,” Kelly said. The mice become overweight, and develop high blood sugar levels and reduced insulin release, as expected before the onset of type 2 diabetes.
We aim to help doctors to make better decisions. That can cause insulin resistance, which can lead to diabetes.” Olson’s team now aim to assess how the path of fat cells is disrupted by imbalances