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Association of Diabetic Neuropathy with Duration of Type 2 Diabetes and Glycemic Control. – PubMed

The EURODIAB IDDM Complications Study involved the examination of 3250 randomly selected insulin-dependent diabetic patients, from 31 centres in 16 European countries. Forty inpatients (23 male, 18 female, age range 18 – 70 years) with a history of type 1 or 2 diabetes and polyneuropathy of not longer than two years, were included in the study. Seventeen patients with chronic Charcot joints, 11 patients with a history of neuropathic foot ulceration, 14 diabetic control subjects, and 11 normal control subjects were studied. The degree of hyperglycemia was assessed by measurement of fasting plasma glucose and glycosylated hemoglobin concentrations. The mean glycated haemoglobin level was assessed on 8.53±1.87%. As the nerves are often damaged first, some people with nerve damage don’t have any symptoms initially due to a loss of feeling. Both acupuncture styles, however, lowered pain according to the McGill Short Form Pain Score.

Data were analyzed in SPSS v. Furthermore, a mean HbA1c of more than 8.5% will result in significant deterioration in electrophysiology. At the beginning of the EDIC study, prior intensive therapy reduced the odds of having symptoms and signs of neuropathy using MNSI criteria by 64% (P = 0.0044) and 45% (P < 0.0001), respectively, with similar odds reductions observed for both neuropathic symptoms (51%, P < 0.0001) and neuropathic signs (43%, P < 0.0001) across 8 years of EDIC follow-up. Two authors abstracted data from all included studies with a standardized form. Furthermore, we assume that the processing of subjective symptoms of the disease and the generation of the HEP share some common neuronal pathways. The mean (standard deviation [SD]) duration of diabetes was nine years (6.76), BSF levels 7.98 mmol/l (2.18), BSR 9.5 mmol/l (3.19), and HbA1c 6.5% (2.18). “Let’s talk about reducing our carbohydrate intake and increasing our physical activity and just taking control of our blood sugars as one of the best treatments to treat neuropathy and many of the other complications,” Steve says. Duration since the diagnosis of diabetes and HbA1c levels were significantly associated with the diagnosis of neuropathy in diabetics.